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Take a missed dose as soon as you think about it. If it is close to the time for your next dose.skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses.

SINEMET is indicated in the treatment of Parkinson’s disease.post-encephalitic parkinsonism.and symptomatic parkinsonism that may follow carbon monoxide intoxication or manganese intoxication.

Because both therapeutic and adverse responses occur more rapidly with SINEMET than with levodopa alone.patients should be monitored closely during the dose adjustment period. Specifically.involuntary movements will occur more rapidly with SINEMET than sinemet plus price levodopa. The occurrence of involuntary movements may require dosage reduction. Blepharospasm may be a useful early sign of excess dosage in some patients.

Trihexyphenidyl ( Artane ) and benztropine ( Cogentin ). These drugs restore the balance between two brain chemicals.dopamine and acetylcholine. That eases tremors and muscle stiffness in people with Parkinson’s. But these medications can harm memory and thinking.especially in older people. Because of that.doctors rarely prescribe them today.

Carbidopa may also reduce nausea and vomiting and permit more rapid titration of levodopa.

Ataxia.extrapyramidal disorder.falling.anxiety.gait abnormalities.nervousness.decreased mental acuity.memory impairment.disorientation.euphoria.blepharospasm (which may be taken as an early sign of excess dosage. consideration of dosage reduction may be made at this time).trismus.increased tremor.numbness.muscle twitching.activation of latent Horner’s syndrome.peripheral neuropathy.

Sporadic cases of a symptom complex resembling neuroleptic malignant syndrome (NMS) have been reported in association with dose reductions or withdrawal of certain sinemet plus price sinemet plus price such as levodopa.carbidopa sinemet plus price.or carbidopa levodopa extended release. Therefore.patients should be observed carefully when the dosage of levodopa is reduced abruptly or discontinued.especially if the patient sinemet plus price receiving neuroleptics.

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